CLINICAL PATHOLOGY CONTENT SPECIFICATIONS
MOLECULAR GENETIC PATHOLOGY

I.Inherited diseases
 Newborn screening
  
II.Infectious Diseases
 HPV testing and cervical cancer
 GC and Chlamydia screening
 HIV measurements—bDNA vs. PCR
 HCV genotyping
  
III.Molecular Oncology
 Gleevec resistance
 Gene expression profiling and applications in tumor classification and determination of prognosis
 Hemato-lymphoid neoplasms, Myelodysplastic Syndromes, Chronic Myeloproliferative Disorders
  
IV. HLA/Transplantation
  
V. Pharmacogenetics
  General principles (e.g. P450 testing and warfarin therapy)
   
VI. Molecular Techniques
  CGI
  Multiplex analysis
  Real-time PCR
  Basic techniques of genetic testing (e.g., PCR, restriction endonuclease cutting of DNA at specific sites, etc.)
  Nucleic acid detection methods for infectious agents (e.g. chlamydia, gonococcus, hepatitis C, HIV, etc.)
  Methods and method interferences
     PCR/RT-PCR
     FISH
   
VII. Management/Quality Improvement
  Rules and regulations for molecular genetic testing (e.g. informed consent)

This page was last modified on February 13, 2008.